• Legacy perfluoroalkyl acids and their oxidizable precursors in plasma samples of Norwegian women 

      Miranda Fernandes Coelho, Ana Carolina; Cioni, Lara; Van Dreunen, Wendy; Berg, Vivian; Rylander, Karin Charlotta Maria; Urbarova, Ilona Halva; Herzke, Dorte; Sandanger, Torkjel M (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-06-12)
      Humans are exposed to perfluoroalkyl acids (PFAA) mainly through direct pathways, such as diet and drinking water, but indirect exposure also occurs when PFAA precursors break down to form legacy PFAA. Exposure to PFAA precursors raises particular concern, as neither the exposure nor the precursors themselves have been well described. In the present study, we aimed to assess the indirect contribution ...
    • Total Oxidizable Precursors Assay for PFAS in Human Serum 

      Cioni, Lara; Nikiforov, Vladimir; Miranda Fernandes Coelho, Ana Carolina; Sandanger, Torkjel M; Herzke, Dorte (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-23)
      Per- and polyfluoroalkyl substances (PFAS) are a class of chemicals including over 4700 substances. As a limited number of PFAS is routinely analyzed in human serum, complementary analytical methods are required to characterize the overlooked fraction. A promising tool is the total oxidizable precursors (TOP) assay to look for precursors by oxidation to perfluoroalkyl acids (PFAA). The TOP assay was ...